With United unable to sign a replacement, the pressure will be on 21-year-old England forward Marcus Rashford to deliver the goals in a more central role than he has previously operated in.
Following is a match by match look at the English Premier League's weekend fixtures:
Just hours before England retained the Ashes at Old Trafford by drawing the third Test against Australia, a "drunk" Monty Panesar 'urinated' on bouncers after being thrown out of a nightclub in Brighton in the early hours of Monday and fined by the police.
Liverpool cranked up the pressure on West Ham United manager Slaven Bilic with a 4-1 victory at the London Stadium, while Burnley's remarkable start to the Premier League season continued thanks to a 1-0 victory at Southampton on Saturday.
Oscar-winning British filmmaker Richard Attenborough, renowned for his critically-acclaimed biopic on Mahatma Gandhi, has died. He was 90.
Everton have agreed to sign Barcelona's Colombia centre back Yerry Mina for an initial 30.25 million euros ($34.97 million) and have also taken the club's midfielder Andre Gomes on loan, the Spanish champions said on Thursday.
Liverpool head to United with widest gulf in years
Mohamed Salah was inevitably on the scoresheet as Liverpool took full advantage of the inactivity of their top-four rivals to thrash West Ham United 4-1 at Anfield and provisionally move into second in the Premier League.
News of all that's transpired on and off the football field
Chelsea manager Maurizio Sarri said having Eden Hazard in such unstoppable form makes winning "easy" but appears almost resigned to losing him.
FA Cup: Arsenal end Lincoln's adventure
News of all that tranpired on and off the football field.
The sport's governing body (WA) said that with immediate effect and for elite competition only, road shoes must have soles no thicker than 40mm and not contain more than one rigid, embedded plate.
Hate it or love it, you can't ignore it -- here's a look at the latest in tattoo designs from across the world.
Liverpool moved into the Champions League qualifying spots after a 3-0 win at Burnley on Wednesday took them above Leicester City and into fourth place with one round of Premier League matches remaining.
Goals from Curtis Davies and Robert Koren earned HullCity a place in the FA Cup quarter-finals with a 2-1 replay win at home to Brighton and Hove Albion on Monday.
Images from the English Premier League matches played on Saturday
Images from Sunday's action in the Premier League.
Holders Manchester City began their assault on the FA Cup with a 4-1 victory over fourth-tier Port Vale but Manchester United and Wolverhampton Wanderers face an unwanted replay after drawing 0-0 at Molineux on Saturday. Goals from Oleksandr Zinchenko, Sergio Aguero, Taylor Harwood-Bellis and Phil Foden made it a routine day for City, although Tom Pope had equalised for a Vale side sitting 74 places lower in the standings.
Odisha Chief Minister Naveen Patnaik has cancelled his participation in a seminar at the Sussex University where he was scheduled to deliver a lecture on Monday amid claims by rights groups that he changed his programme fearing demonstrations against him.
Arsenal extend Aubameyang stay with new three-year deal
Lacazette fired the Gunners ahead in the eighth minute after poor defending by the home side before new signing Gabriel made it 2-0 in the 49th and Aubameyang put the icing on the cake with a superb shot into the top corner.
Chelsea have signed Germany's highly-rated attacking midfielder Kai Havertz from Bundesliga side Bayer Leverkusen on a five-year contract, the Premier League club announced on Friday.
Manchester United's current malaise was laid bare as they struggled past third-tier Rochdale 5-3 on penalties after a 1-1 draw in the League Cup third round.
London clubs' erratic start to the Premier League season improved with victories for Chelsea, Tottenham Hotspur and Arsenal on Saturday but Manchester sides continued to make the running, with City and United the top two.
England government says no elite sport in country at least until June 1. Cricket and rugby authorities in England have said their sports will not resume until July.
Here are eight images that prove we live in a mad, mad world.
England's World Cup victory over Sweden on Saturday was heard throughout the land.
Manchester City displayed champions' swagger as they roared clear at the top with a 5-0 trouncing of Burnley but it was drama which engulfed their neighbours Manchester United and Jose Mourinho that dominated the Premier League agenda on Saturday.
Following is a match by match look at the English Premier League's weekend fixtures:
Mathew Ryan asked his family if anyone wanted to come and watch him play in the World Cup in Russia, there was an enthusiastic response - from 27 of them.
A video of the incident showed that Taison stuck his finger up at a section occupied by Dynamo fans and then hoofed the ball into the stands.
Pep Guardiola hailed Sergio Aguero's 'unique' skill of sniffing out chances in front of goal, and David Silva's ability to ghost past defenders
Liverpool face Spurs in the game of the weekend, a day after title rivals Manchester City travel to struggling Fulham.
This season's FA Cup favourites Tottenham Hotspur were held to a 0-0 draw at third tier Stevenage Sunday but Liverpool laid their claim to be the real frontrunners with a 6-1 fifth-round thrashing of Brighton & Hove Albion.
Like Chelsea, the humble Hertfordshire club, whose only season in European football was 35 years ago, completed their third victory from three games on Sunday, when they beat Crystal Palace 2-1 to add to victories over Brighton and Burnley.
Leicester City's traumatic week ended with a 1-0 win at Cardiff City although the result was never the chief concern on a day when the tributes flowed for the Midlands club's late owner Vichai Srivaddhanaprabha who died in a helicopter crash.
News of all that's transpired on and off the football field.
Debutant Owen Hargreaves scored his first goal for more than three years and Mario Balotelli grabbed his first of the season as Manchester City beat holders Birmingham City 2-0 in a League Cup third round tie at the Etihad Stadium on Wednesday.
Premier League quartet Sunderland, Norwich City, Queens Park Rangers and Swansea City were bundled out of the League Cup in the second round on Tuesday.